Research field : Functional Organic Chemistry
Department of Chemistry, Okayama University, Tsushimanaka, Kita-ku, Okayama 700-8530, Japan
B.Sc. (Hiroshima Univ., 1992), M.Sc. (Hiroshima Univ., 1994), Ph.D. (The Graduate University for Advanced Studies, 1997)
- JSPS Research Fellow (1996.4-1996.8, The Graduate University for Advanced Studies)
- Research Associate of Chemical Resources Laboratory, Tokyo Institute of Technology (1996.9-2004.3)
- Associate Professor of Department of Chemistry, Okayama University (2004.3-2010.3)
- Professor of Graduate School of Natural Science and Technology, Okayama University (2010.4-)
- Organic Synthesis Catalyzed by Homogeneous Organometallic Complexes
- Activation of Unreactive Chemical Bonds such as the C-C, C-Si, and C-B bonds
- Application towards Functional Materials
- Isolation and Determination of the Structures of the Important Intermediates in the Catalytic Cycles
My current research interests are organic synthesis mediated and/or catalyzed by organometallic compounds and their application towards functional materials. In particular, activation of the chemically unreactive bond, e.g. the C-C, C-Si, and C-B bonds is one of the stimulative subjects. The unreactive bonds might be cleaved by the highly unsaturated organometallic species and the subsequent C-C bond-forming reaction, for example, the cross-coupling ractions, can be attained. Furthermore, the synthesized organic molecules are used as the useful functional materials such as liquid crystals, electroluminescent materials, and lithium ion batteries. On the other hand, it is worth determining the structures of the real catalytically active species in the catalytic cycles. Thus, the isolation and determination of the structures of the intermediates by X-ray diffraction are also investigated.
- 1. Highly Regio- and Stereoselective Synthesis of Multi-alkylated Olefins through Carbozirconation of Alkynylboronates and Sequential Negishi and Suzuki-Miyaura Couplings Y. Nishihara, Y. Okada, J. Jiao, M. Suetsugu, M.-T. Lan, M. Kinoshita, M. Iwasaki, and K. Takagi
Angew. Chem. Int. Ed. 50, 8660-8664. (2011).
- 2. Enantioseparation of Doubly Functionalized Polar Norbornenes by HPLC and Their Ruthenium-Catalyzed Ring-Opening Metathesis Polymerization
Y. Nishihara, Y. Doi, S. Izawa, H.-Y. Li, Y. Inoue, M. Kojima, J.-T. Chen, and K. Takagi
J. Poly. Sci. Part A: Pol. Chem. 48, 485-491 (2010).
- 3. Regio- and Stereoselective Synthesis of Multi-Substituted Vinylsilanes via Zirconacycles
Y. Nishihara, D. Saito, K. Tanemura, S. Noyori, and K. Takagi
Org. Lett. 11, 3546-3549 (2009).
- 4. Synthesis and Ion Conductive Characteristics of Inorganic-Organic Hybrid Polymers bearing a Tetraarylpentaborate Unit
Y. Nishihara, M. Miyazaki, Y. Tomita, Y. Kadono, and K. Takagi
J. Poly. Sci. Part A: Pol. Chem. 46, 7913-7918 (2008).
- 5. Zirconocene-Mediated Highly Regio- and Stereoselective Synthesis of Multisubstituted Olefins Starting from 1-Alkynylboronates
Y. Nishihara, M. Miyasaka, M. Okamoto, H. Takahashi, K. Tanemura, E. Inoue, and K. Takagi
J. Am. Chem. Soc. 129, 12634-12635 (2007).